APOE and mild cognitive impairment: the Framingham Heart Study

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APOE and mild cognitive impairment: the Framingham Heart Study.

BACKGROUND The risk apolipoprotein E-4 (APOE4) poses for mild cognitive impairment (MCI) may vary based on the neuropsychological definition of MCI. SETTING A community-based cohort study. METHODS Using two psychometric neuropsychological impairment definitions, we examined APOE4 and prevalent MCI among older adults or pre-MCI among middle-aged adults. Neuropsychological, clinical and genet...

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Alcohol consumption and cognitive performance in the Framingham Heart Study.

Recent studies have indicated that moderate alcohol intake may be beneficial to cognitive functioning in women, although not necessarily in men. Data from the Framingham Heart Study, a large, prospective study of cardiovascular disease in Framingham, Massachusetts, were used to examine the relation between alcohol consumption and cognitive ability. The major research question was whether a diff...

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Framingham Risk Score and the Risk of Progression from Mild Cognitive Impairment to Dementia.

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ژورنال

عنوان ژورنال: Age and Ageing

سال: 2014

ISSN: 1468-2834,0002-0729

DOI: 10.1093/ageing/afu183